MathBio Seminar | Tyler Meadows | Mathematical models for the growth of bacterial persister cells
Apr 3, 2025
2:30PM to 3:30PM
Date/Time
Date(s) - 03/04/2025
2:30 pm - 3:30 pm
Speaker: Tyler Meadows (Queen’s University)
Research area: Microbial ecology, mathematical epidemiology
Location: Hamilton Hall, Room 410 & Zoom
Title: Mathematical models for the growth of bacterial persister cells
Abstract: Within some colonies of bacteria, bacterial persisters exist as a subpopulation that is seemingly immune to antibiotics. However, these cells are not genetically distinct from the rest of the population. Although the mechanism through which they avoid being killed by antibiotics is reasonably well understood, the method through which these persister cells arise is still debated. Their existence is typically viewed as a genetically encoded bet-hedging strategy in response to fluctuating environments. We will investigate a model that takes an alternative approach, viewing the persister trait through the lens of epigenetic inheritance.